Magnesium, Muscle Pain and Lupus

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Magnesium, Muscle Pain and Lupus

Reference: Romano TJ. Magnesium deficiency in systemic lupus erythematosus. J Nutr Environ Med 1997; 7:107-11.

Summary: Erythrocyte magnesium levels were measured in 25 patients with systemic lupus erythematosus (SLE) and 12 with osteoarthritis (OA) who served as controls. Thirteen of the SLE patients met criteria for fibromyalgia and none had kidney complications. None of the study participants were taking magnesium or any other nutritional supplements. The erythrocyte (but not plasma) magnesium level was significantly lower in SLE than OA patients. It did not vary significantly between SLE patients with and without fibromyalgia.

A single case study was presented involving a 35 year old white woman with SLE. She was taking prednisone and azathioprine and had developed myalgia. Erythrocyte magnesium proved to be decreased and two courses of Ig magnesium sulfate intramuscular injection each week for six weeks were administered. By the end of the second course all her muscle pain was gone and she was maintained on oral magnesium

Natural Product Research Consultants, Inc.

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By E. Yarnell

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