Shorts: Schizophrenia

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Shorts: Schizophrenia

In 1985, E.P. Heleniak and S.W. Lamola noticed similarities between Pfeiffer's histamine theory of schizophrenia and Horrobin's prostaglandin theory. The type of schizophrenia described in both theories shows the same symptoms: thought disorders, overarousal, grandiosity, paranoia, ideas of reference, hallucination, mania, and a high copper/low zinc ratio. In both types of schizophrenia, methionine, which lowers blood histamine levels, worsens symptoms. The two researchers postulated that low histamine and prostaglandin levels indicate different measurements of the same physiological disorder since prostaglandins and histamine levels respond concurrently to physiological changes. The exact link between PGE-1 and histamine is unknown, but PGE-1 may be part of the system that activates the release of histamine.

Despite the gaps in etiology, the schizophrenia described by Pfeiffer and Horrobin also responds to the same treatment. A protocol of folic acid, vitamins C and B6, niacin, zinc, penicillamine (a copper chelating drug), a high protein diet, and essential fatty acids found in oils, fish, and/or evening primrose oil produces significant improvement.

Ref. Heleniak, EP, Frechen, DM, Histamine methylation in Schizophrenia, Medical Hypothesis, 1989, 30:167-174.

Townsend Letter for Doctors & Patients.

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By Jule Klotter

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