Schizophrenia: A Proposed Cause & Cure

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Schizophrenia: A Proposed Cause & Cure

Schizophrenia has traditionally been treated as a "reactive" psychiatric disorder, i.e., "Logical but maladaptive reactions to common life events." Sigmund Freud, however, "...concluded that some aspects of schizophrenia were beyond a purely psychological understanding." This paper will expound on and validate that shrewd observation of the early century. It will present the argument for the genesis of schizophrenia being of the "process" or chronic type caused by a physical infection whose secretions provoke a chemically induced biological reaction.

What is our point of departure? Let us review what the possible infectious microbes are in very liberal and broad terms that are really old classifications of the Five Kingdoms defined by biologists. We note that biologists claim there are the Five Kingdoms (some say a further division is needed claiming Six Kingdoms). Neither the Five nor the Six include the viruses. Biologists deal with living things and viruses are dead. Viruses are dealt with as an addendum because viruses affect living cells. Doctors' needs are different: their laboratory is the living human body: their patient.

Doctors' perspectives are best suited with only three major divisions of infectious microbes which must include viruses. No less and no more than three. Each has infinite branching to satisfy those who want variety. Those three simplified branches of infectious microbes will be: the Viruses, the Bacteria and Fungi.

Viruses are dead DNA/RNA programs that go active when they pierce a living cell. We will accept the biologist's definitions. These viruses are lifeless cell takeover programs that use the nucleus of the host's cell (its yolk?) to replicate their viral DNA/RNA codes into new viral clones. They can be hot or cold infestations (feverish or non-feverish). They can be pan-systemic or a singular, well-defined tumor, i.e., wart. They function best in an unlimited, direct blood supply. Some organize a very intense venous system or a tuber-like root structure for blood nourishment if they are not swimming free in the blood, i.e., hematogenous. The blood is really just another body organ like the brain, kidney, or like its closest relative, the liver. The body does a remarkable job of defending itself in a week to ten days for many of these viruses. A defensive fever is commonly associated with these infections. "Cooking" the virus is one of the body's major weapons for combating a virus. Somehow the body being chilled below normal temperature seems to make the patient much more susceptible to a new viral infection and the recurrent fever blisters, Herpes #1/#2.

Aspirin is the universal anti-viral chemical. Aspirin is the best chemical to eliminate warts, (Verruca Vulgaris) and is given in a hard skin penetrating solvent (ether). Aspirin is given for all cold or flu symptoms of viral origin, with bed rest. A less noted potassium ion (K) and iodine seem to both be antiviral. The iodine and potassium are agents that I think can help the human body's anti-viral armory. This remotely implies the possible use of lithium ion usage as a helper as well as the halogens other than iodine. Lighter and more active members of the same Periodic Chart column replace the heavier atoms. Sodium is used for nerve transmission and Li would displace it altering synapse transfer and alter things like the Hebe-gebes (mania, puberty).

An auto or serum inoculation (internal body defense or injected/oral) is a brilliant method to prevent or subdue a viral infection in the future no matter how intense that particular virus' assault. This is why a cold/flu vaccine is always being modified: the old one is now rendered inert by those that had it or one extremely close to its configuration. Exceptions to this are found: an example noted is the herpes #1 or #2 which are recurrent.

The bacteria are really animals of a very primitive sort. The classic definition of an animal is that it is an organism that produces a form of metabolized nitrogen as urea which it can no longer use. For the sake of brevity, we will include those microbes that biologists will classify as other than Monera. These are Protsita and leave the door open to any primitive, Micro-Animilia. Intestinal worms (Nemathelminthes and Platythelminthes but Annelida doesn't seem to be important) are curiously treated with an anti-fungal because they often have a fungus in their digestive tract. Examples of anti-fungal agents are the tri-cyclenes and nicotine. All the bacteria should be called fauna and treated as such with their own individual, minor idiosyncrasies.

The more primitive the bacteria the more closely it resembles the primitive fungi. Blue-green algae are a bit of both bacteria and fungi. It's like a fungus that has learned to exist in a saline solution and a bacteria that can make chlorophyll. The differentiating attributes of bacteria (fauna) from fungi (flora) is the use of B12 in place of the fungi (flora) chlorophyll, which in primitive bacteria and fungi are still interchangeable. When we try to stop or reduce the nutrients for a fungal growth by minimizing the intake of chlorophyll, we must also limit the intake of vitamin B-12, its look-alike with the center atom changed to cobalt. Fungi can do well in a very cold environment: bacteria become inert when below 40øF. Note the delicate effects temperature ranges of only a few degrees Fahrenheit have on animal life forms. We really have a blood temperature of 526øF above absolute zero, a 1% change makes us sick, and a 10% reduction stops bacterial growth. Fun gi do well even with another 10% reduction. The exceptions are that some bacteria stay alive up to 838ø absolute temperature in dry heat.

Since the bacteria are animals, they can live in the bloodstream just like the virus. With that fantastic food supply they can propagate very rapidly while secreting their toxins. This fast cell division means they are a high heat liberating reaction or a rapid metabolism. I don't think this is a measurable rise, I think the body uses other reactions to generate the associated fever. The body's defense must be quick and intense to be a good defense against bacteria. A lot of fungi don't make a difference if they get cured this year or next. Is it life threatening to have a wart on your hand? Not in the least. A bacterial infection is different; they can grow, doubling their numbers many times a circadian cycle. The patient's body can't compete with the flood of the growing bacteria, they quickly permeate and poison the patient. Bacteria are the fastest killers among the infections because of an overwhelming population explosion though fungal toxins can be a thousand times more p otent on a molecule to molecule basis. The bacteria also exude a series of different toxins (that seem to be acidic). The body's defense for both bacteria and viruses is a fever.

The bacteria have a few weak spots. All will succumb to a rapid pH change (the stomach sanitizes food in this way), and bacteria are extremely sensitive to the toxic fungi output, i.e., penicillin. Clean living (detergents, bleaches), cooking food (steamed for a given time plus pressure if possible), acid/base swing and fungi are the quick and sure ways to defeat almost any bacteria easily.

Let's play with the concept of the stomach eliminating the bacteria with a pH change and see what is the predictable corollary. The gut is under constant and unremitting assault by bacteria (as well as by the viral and fungal microbes). A normal gut pressurizes, in flux, by closing both valves and squeezing the contents with enzymes and lowering the pH, i.e., making the contents very acidic. Then it relaxes and secretes a base to neutralize the contents or perhaps make them slightly basic, all in a short time. This is a healthy gut system to either a chemical engineer or a doctor. Now introduce the factor of a nervous stomach: one that constantly dribbles acid, keeping the pH level fairly constant, day and night. Is it the acid that eats the lining? I doubt it. Just imagine an acid-loving bacteria finding this steady state environment. Bacteria can even live in jet fuel, a very inhospitable environment.

This should be the first stage of an ulcer, a bacterial infestation. Step two: fungi find the dead skin of this raw ulcer and takes it away from the bacteria, leaving the bacteria to exist in only the edge surrounding site as in the infection of Tinea Pedis. Therefore to treat an ulcer of the stomach, one should use: Stage one: a bactericide; Stage two: a bactericide with a fungicide and get the stomach to a normal pH cycle. Stomach ulcers should really all be treated as a Stage Two situation; that solution handles either stage one or stage two.

Considering Schizophrenia

For the sake of this discussion, let's consider the cause of schizophrenia to be fungal. Let's make the argument and predicate this survey on the cycle of that mysterious illness from the viewpoint of the illness being caused solely by fungi. We will test this hypothesis that must cover the many idiosyncratic oddities that seem to go with this most terrifying sickness: a mind out of the control of its owner as if pirated by demons.

What are the noted attributes that schizophrenia is caused by fungal toxicity? What are the indicators that this illness is even an infectious disease? All schizophrenia is the process (chronic) schizophrenia v. reactive (induced by external factors or learned) schizophrenia. Further, that the cause of schizophrenia, in its earlier stages, is not misconnected or shorted-out "wiring" (synapses firing through faulty myelin sheaths) in the brain, but that it is of chemical origin caused by secretions of a fungi. We will not cover the un-learning/re-learning necessary for any recovery of any habituated (associated reactive aspects) lifestyle caused by this illness of process schizophrenia.

Other indicators that schizophrenia is fungal? Steroid usage is noted which is strongly pro-fungal along with chronic nicotine, caffeine, L-dopa etc. What about caffeine? Is caffeine possibly mildly anti-fungal? Let's look at the molecule profile of caffeine comparing it to the Indole (a pro-fungal molecule), and severely modified, anti-fungal, nicotine molecules. Caffeine is a severely modified indoled molecule with several important indole atoms exchanged for other atoms, but retaining the indole shape. It passes the blood/brain barrier but does not promote fungal growth: note that coffee grounds left damp in the open sit a long time before decomposing.

A wild card thrown in at this point is an illness that could now have a fungal implication, never heretofore considered as such: the cardiovascular illness of myocardial infarction which is statistically associated with schizophrenia patients. This may just be an effect caused by the horrid medicines given, a patient's lifestyle, or it might have something to do with a fungus. Further research is needed. An interesting thing about medicine is the force and volume of questions that boomerang back whenever we toss out the smallest suggestion.

What illnesses schizophrenia is associated with provides us with a clue. LSD-25, a fungal generated toxic indole, can give results that are indistinguishable from schizophrenia. What other indicators do we have? Schizophrenia has a higher prevalence in patients that have severe fungal illnesses such as Lupus, M.S., deficiencies in B-1, B-3 (nicotinic acid, a fungicide), prophyria (the pyrole half of a fungi indole molecule with one type of modified-urea attached).

What is different about a fungal infection? It uses the nitrogen offered it by fauna which it changes into a form that the kidneys can't pass. The fungal infection is non-feverish. Note that there is no fever ever associated with a schizophrenia episode with one significant, unnoticed exception -- that of an initial preparation of the site for a fungal infestation. If you listen very closely, you will hear that most patients, with any chronic illness, think it began with some other illness or mechanical injury. This bacterial, viral or mechanical trauma initiates and preps the site that any roving fungi (spore) infection can now take over and dominate.

One unnoticed indicator of a fungal infestation is that it metabolizes the urea that the human body emits to feed itself and then secretes a modified urea that the body can't handle. Gouty arthritis is a good example. Note that a fungus on a topical surface such as Irritable Bowel Disease, psoriasis, sinusitis, etc., can drain into a void and not cause toxicity to the body due to its inability to be processed and pass on to the kidneys. So if there is a fungus causing schizophrenia where is the modified-urea that the body can't handle?

To answer the modified-urea question we must know where the fungal infection is sited. Since the fungi are so potent, only a very few are needed. In fact such a small number of fungi are needed that they and the modified-urea could escape any detection other than an implied existence. Since the hypothetical toxic fungus indole secretion can pass the blood/brain barrier, the fungal infestation could even be under that patient's toenails and the fungi's extreme cell-wall penetrating toxins could find their way to the most sensitive of all human organs, the brain. Not knowing where the fungi is sited or the size and number involved, hence the place and volume of the fungi-secreted modified-urea, makes looking for the fungal site impossible. In gouty arthritis the fungal site is obvious.

There is a hint in the voluminous medical literature to show where we should look if we prescribe a small dose of logic for ourselves. The blood/brain barrier should stop most fungi. The closer the fungal site is to the brain, the more effective an unnoticeably small number of fungi would be. Don't forget, fungi-like steroids and cortisone was first culled from the outside surface of the brain. If the blood/brain barrier wasn't there, neither would be the brain, it would be covered with fungi and putrefy and mortify like a rotting log. This concept would put the fungal site at or near the stalk of the brain just outside the blood/brain barrier. The exceedingly small infestation would now produce such a small amount of modified-urea as to be unnoticed. The thermographs of schizophrenia patients show lesser activity at most sites of the brain, but at the blood/brain barrier, more activity or heat is indicated. That wasn't so hard was it? It is a point to first look for a fungus.

Note that one of the characteristics of some severe fungal infections is that the patient never gets a cold. We know fungi provide protection from bacterial infections but there is also some protection from viruses too. Why, I don't have a clue.

What provokes a fungal growth, hence schizophrenic episode?

Lactic acid seems to be a provocateur par excellence. When I had my irritable bowel disease, extreme muscle work caused the illness to get very severe. Schizophrenia patients given a lactic acid injection get schizophrenic episodes: normal people do not. This is a definitive chemical test for a very hard-to-define illness. When schizophrenic patients are on the standard schizophrenia medicine, they do not have these attacks with lactic acid injections. Lactose sugar is another fungal activator or provocateur (pill binder is made out of milk and not to be confused with lactic acid). Have you ever heard of a woman getting yeast infection after being treated with a strong dose of one of the penicillins? This is very common.

What causes a steroid imbalance in the human body? Stress, puberty, pregnancy, post-partum, medicines, etc. Great stress is a major producer of that chemical. Look at all the mental problems of the soldiers that have had extraordinary stress and the problems they end up with as "survivors' syndromes," "combat fatigue," etc. If this long exposure to steroids doesn't get metabolized in work, fight or flight, they seem to make way for a fungal infection to establish and grow. First the body reacts to steroids in a positive way and then it's payback time. When I suffered from the fungal infection of ulcerative colitis, intense stress made me better immediately. A week or two later, I would be a disaster, the illness would definitely have the upper hand. When schizophrenic patients have a stress period, a week or two later is their payback time. Note the similarity, please.

Our typical fungus needs chlorophyll by definition because it is flora. And being extremely primitive, it can use the fauna B-12 almost interchangeably.

Another sure-fire sickness maker is to take a fungicide for an extended period of time, like nicotine or any of the tri-cyclines, and then stop without using an anti-fungal regimen. This is a guaranteed fungal infection, it's just a matter of which fungus where and how strong the fungus infestation will be. The breaking of the smoking habit, incorrectly done, can be the greatest health risk America could ever face. Most cases of ulcerative colitis are associated with stopping smoking.

Another anti-fungal is iodine (as noted, it seems to be anti-viral also) but much weaker and milder than chloride as an anti-fungal. Iodine is a powerful anti-fungal (and in what seems to be higher doses, also anti-bacterial). I consider its reduction below the RDAs as a proposed cause of a higher rate of fungal infections like schizophrenia, asthma, IBD, arthritis, lupus, etc. Modern day dietary reduction of NaCl with iodine is noted also. What other vitamin chemistry promotes fungal infections? Vitamin A is a steroid imitator. Bacterial growth and subsequent demise prepares the sites of the body for further fungal infection. Where a bacteria can co-exist with fungi in a patient, these bacteria can cause great and rapid damage to the patient as in Mega-colon in the ulcerative colitis patient.

How about alcohol? What should its theoretical effect be to a schizoid patient? As always, let us go to the source. The common source of alcohol (methyl carbinol) is yeast, a major subdivision of fungi. Alcohol is anti-bacterial and because it comes from a fungus it is therefore pro-fungal. Alcohol blood dilution (drunkenness) provides a temporary calming effect on the schizoid patient. Because any bacteria in contact with alcohol is suppressed, the rebound growth is increased for the fungi which intensifies the future episode of schizophrenic illnesses. The greater the fungal infestation, the more devastating the schizophrenic episode: alcoholism is associated with schizophrenia. The anti-fungal chemicals used to fight schizophrenia are indicators as to the cause of this terrifying disease.

One of a galaxy of the tri-cyclines is #2186, chlorpromazine. Miscellaneous other near tri-cyclines only slightly less related to the molecule #7220 is carbamazepine (#1783), a tri-cycline with an extra atom in the center ring. We must look at the root of any chemical to get a handle on its function and use. Also look at mercurochrome (Merbromine #5757) which is interesting because it at least provides a little variety in the repetitive tri-cyline theme by using the old standby mercury (Hg). In a micro/micro dose, Hg can be very effective but long term use can be devastatingly toxic. To be effective, it has to kill something, so Hg is called dangerous. Misused it surely is, but is it safe to stay ill? So Hg based medicines are called a health hazard (patient rights have expired) and lets a drug company make money with the new chemicals that don't work near as well. How else can the new chemicals make more profit? The price is higher just because only the patent holder can issue a permit to make them. Also, it takes more than one drug to do the job and many more treatments, and the new drugs which have horrid side effects, require a doctor's prescription and now the still ill patient has to spend more time in the hospital. Medication, hence cure, that should cost a dime now costs tens of thousands of dollars and even the life of the patient.

Note that young children who get IBD's have a 30% to 40% mortality rate by the time they reach the age of majority. This is when they receive the "Best of the FDA/AMA's Medical Care." This just shows the seriousness of the illness. It takes only one dollar of chemicals to cure each child, which cannot be administered within the FDA/AMA guidelines.

The profit motive cannot help but make the most sincere doctors prescribe expensive drugs and further tests (just to be sure the patient is safe). If a doctor fails to play this game, the general microbe being inferred indirectly, then that doctor is liable to feed the vultures who really regulate medicine and the FDA/AMA. Because the precisely correct and approved chemical trade name (active patent) will be spelled very differently, though the chemicals will show 90% commonality and really be interchangeable, a doctor will be Keel-hauled by our judicial system to teach him a lesson in the importance of greed to our GNP. As the Japanese say, "The high nails will be driven down." This is done at the cost of multiplying the danger to the patient and the cost to the general public.

The molecule derivatives of the Tri-C's are damaging to the liver whereas the nicotine is not. The advantage of the tri-C's is due to the strong numbing or blocking effect on the brain cells which seems to be needed in many schizophrenic episodes. This gain is often at the expense of severe and even fatal damage to the liver in long term tri-C usage. The knowledge of what is really going on can help the doctor/patient minimize the use of the dangerous but necessary tri-C's.

On examination of schizophrenic episodes we find the following occurrence repeatedly: severe stress, a 14-day wait for the episode to occur (10 to 12 days for the aura?). How does our model of a fungal infection fit into this? We need to find out how long it takes a spore to mature to an active fungus in the human body to answer that question.

Steroids strongly promote fungal growth. Stress releases a massive amount of steroids. If these steroids are not metabolized or used in the body, the fungi use them and grow, then when their growth is not sustained, die and release their toxins. The toxins of fungi seem to be based on variations of the molecule #4869, the indole molecule. The most notorious example of this indole base is the molecule #5507 (LSD-25) which is made by a fungus originally. It so happens that a person on LSD-25 can be indistinguishable from a schizophrenia patient suffering a schizophrenic episode.

Nicotine has the virtue of metabolizing into vitamin B-3, which is noted as a chemical to treat schizophrenia. Note that many schizophrenic patients show a calming of episodic events while smoking. This use of nicotine allows a schizophrenia patient to focus. Isn't this strange, a stimulant calming a person? And that stimulant just happens to be anti-fungal? And the other chemicals used to treat schizophrenia just happen to be anti-fungal also?

There are some other odd illnesses that seem to be prevented by or respond to anti-fungal agents such as nicotine and the tri-cyclines. Nicotine users have been noted to have less Alzheimer's, Parkinson's, Sleep apnea, IBD's, Asthma's, etc. by Dr. Jarvik. A strong argument can be made for each of the foregoing illnesses to be caused by a low or non-feverish fungal infection.

In "Menke's Kinky Hair" syndrome the body cannot absorb copper. A trace of copper, a noted fungicide, cures the problem. That is it stops the progress of the illness, which is in the brain, but doesn't repair any brain damage. Doesn't Cu uptake get reduced by alcohol? Don't people with arthritis (a fungal illness) often swear by copper bracelets?

Certain things that have been noted about viral infections are that a "one pill cure" or "one serum injection" is possible. This has led many to think that all illnesses, even if they are not a virus can be cured with one pill. The treatment of a bacterial infection in just a few days (commonly ten days) has bolstered this "pipe dream" that a single, correct pill will cure "it," whatever "it" is, even though constant cleanliness and preventive measures are really needed, i.e., a "defensive lifestyle." Hence limiting bacterial infections is really a constant lifestyle of refrigeration, washing, eating right, chlorinated water, and good habits in general.

Fighting a fungus is an ongoing battle or a "defensive lifestyle" too, in the pursuit of good health. Gouty arthritis is a splendid example of long-term management that is effective only with clear insight to fungal treatment and schizophrenia is an obvious and excellent implied infection of fungi whose treatment is using anti-fungal measures with no pro-fungi slip-ups which cannot be done without a broad concept of the cause. The past treatment of this serious illness is strictly trial and error without any overall concept of what is going on as though there was no broad concept available or even hinted at by the chemistry involved.

Those that propose a yeast cause are on track though and it may well be a yeast that is the causative microbe, though the other fungi should still be open for consideration. Treatment without logic schema (compass), is treatment founded on a data base which is now quickly lost in such a fog as to be virtually useless (medicine then becomes a lifeboat without a rudder for which the hull is missing.) This style of treatment totally avoids any unifying theme hence any real chance of a cure due to the lack of reasonable and/or proper diagnoses. A patient or doctor cannot go in more than one direction at once and succeed. Even if one proposes the wrong cause, genetic, chemical, external, microbial, etc., at least the trial and error method will either prove or disprove the advanced theory permitting its refinement or erasure.

Most of today's treatments are more political and seem to lack any solid scientific basis. A scientific basis is where each concept is firmly attached and proved by known scientific cause and effect to a previous established point, making a chain connecting the start to the finish; the cause to the cure. The point of the beginning is always the simple sciences: first year chemistry, first year biology, first year zoology, etc.

In the illness of chronic or process schizophrenia, we suggest the cure to the physical cause to be anti-fungal regimens which can use all the existing anti-schizophrenia chemicals to treat fungi. These medicines prescribed should all be anti-fungal, ie., nor-nicotine and nicotine (very limited usage), Vitamin B-1 through B-6, potassium and lithium, iodine and other halogens, sulfates and sulfur, iron supplements, etc. (copper ions should be included too but I don't know which ones are safe and in what doses.) The chemicals that must be avoided or severely limited are the pro-fungal vitamin A, B-12, D's and K's. Also avoid the strongly pro-fungal pill binder, lactose and any milk products (excepting hard cheeses), and in particular the chlorophylls must be avoided. Heavy or even modest physical workouts must be avoided because they generate lactic acids at a rate that the body cannot handle. This regimen, which uses most of the existing schizophrenic treatments with only slight modification, should be easy, safe and provide results quickly to prove or disprove this contention of a fungi being the cause of schizophrenia.

Correspondence:

David Barnes

215 Christine Dr.

San Pablo, CA 94806

510-223-01592

Fax 510-222-1650

Townsend Letter for Doctors & Patients.

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By David Barnes

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